Recombinant Human IGF-1 Des(1-3) Receptor Grade

Stable lyophilized for at least 2 years at 2-4C

Human Des(1-3) Insulin-like Growth Factor-I (IGF-I) is a 67 amino acid analog of human IGF-I lacking the N-terminal tripeptide Gly-Pro-Glu. Human Des(1-3) IGF-I is more potent than IGF-I, in vitro, and, in vivo . This increased potency is due to reduced binding of human Des(1-3) IGF-I to most of the IGF binding proteins which normally inhibit the biological actions of IGF-I. Human Des(1-3) IGF-I binds to the Type 1 IGF receptor with similar affinity to full length IGF-I. This is a high quality reagent for use in studies on cell growth, IGF receptors and IGFBPs.

Use Protocol #1000 included with product

<0.1 EU/ug