Comparison

Recombinant Human IGF2 Des(1-6) Receptor Grade

Item no. CS-MU020
Manufacturer Cell Sciences
Amount 20 ug
Category
Type Proteins
Format Lyophilized
Specific against Human (Homo sapiens)
Host E.coli
Purity Greater than 95% by HPLC and N-terminal sequencing
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products IGF1A, MGF, IGFI, OTTHUMP00000195084, insulin-like growth factor 1, IGF-IA, IGF-IB, somatomedin-C, OTTHUMP00000195082, mechano growth factor, insulin-like growth factor IA, insulin-like growth factor IB
Available
Description
Human Des(1-6) Insulin-like Growth Factor-II (Des(1-6)IGF-II) is a 61 amino acid analog of human IGF-II, lacking the first six N-terminal amino acids. This analog of IGF-II binds to the Type 1 and Type 2 IGF receptors with similar affinity to IGF-II. Human Des(1-6)IGF-II exhibits reduced affinity for IGF binding proteins (IGFBPs), which modulate the actions of IGFs.
Biological Activity
Type 1 IGF receptor binding assay: ED50 Less than 50 ng/ml. Type 2 IGF receptor binding assay: ED50 Less than 100 ng/ml. IGF binding protein assay: ED50 Greater than 1000 ng/ml. Stimulation of protein synthesis in rat L6 myoblasts: ED50 Less than 75 ng/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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