Comparison

Synthetic Human IL-21R (NT) Blocking Peptide (aa 20-32)

Manufacturer Cell Sciences
Category
Type Proteins
Specific against Human
Amount 50 ug
Item no. CS-PX206BP
Targets IL21
eClass 6.1 34160400
eClass 9.0 42020190
Available
Description
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Formulation
It is supplied as 200 ug/ml, 50 ug/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM, Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Storage and Stability
Store at -20C, stable for one year.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
available

Delivery expected until 4/18/2024 

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