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Recombinant Mouse MIP1A/CCL3

Recombinant Mouse MIP1A/CCL3

Manufacturer	Cell Sciences
Category	Oncology Neuroscience Neural Signaling By Cell Type Carcinoma Hematology Lymphoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Autophagy
Type	Proteins
Specific against	Mouse
Amount	2 ug
Host	E.coli
Item no.	CS-CRM401A
Targets	MAPKAP1, RPTOR
eClass 6.1	34160400
eClass 9.0	42020190
Available
Biological Activity	The activity is determined by the ability to chemoattract human PBMCs at 1-10 ng/mL.
Description	Macrophage Inflammatory Protein-1 alpha (MIP-1alpha), also known as CCL3, is produced by macrophages and is thought to induce inflammatory responses, including superoxide production by neutrophils. MIP-1alpha can exist as a naturally occurring heterodimer with MIP-1beta and has been shown to have antiviral activity against HSV-1. Recombinant mouse MIP-1alpha is a non-glycosylated protein, containing 69 amino acids.
Endotoxin Level	Measured by kinetic LAL analysis and is typically <= 1 EU/ug protein.
Formulation	Recombinant mouse MIP-1alpha is lyophilized with no additives.
Molecular Weight	7.8 kDa
Reconstitution	Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Storage and Stability	Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.