Synthetic Thymopentin

Lyophilized Thymopentin although stable at room temperature for 3 weeks, should be stored desiccated below -20C. Upon reconstitution TP-5 should be stored at 2-4C between 2-7 days and for future use below -20C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.

Thymopentin, also known as TP-5, is a synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties (corresponding to the amino acids 32-36 of thymopoietin). Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle. Thymopentin has a molecular formula of C30H49N9O9 H-Arg-Lys-Asp-Val-Tyr-OH.

It is recommended to reconstitute the lyophilized Thymopentin in sterile 18MU-cm water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.