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U87MG cells

U87MG cells

Item no.	C0005002
Manufacturer	Addexbio
Amount	One Frozen vial
Category	Oncology Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Cell Lines & Cell Culture Cell Lines By Organ Skin Cancer Bladder Cancer Brain Cancer
Type	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Deng, J. Y., Chen, S. J., Jow, G. M., Hsueh, C. W., and Jeng, C. J. Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas. Chem Res Toxicol, 22: 1817-1826, 2009. 2.Diaz Miqueli, A., Rolff, J., Lemm, M., Fichtner, I., Perez, R., and Montero, E. Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies. Br J Cancer, 100: 950-958, 2009. 3.Frankel, P., Pellet-Many, C., Lehtolainen, P., D'Abaco, G. M., Tickner, M. L., Cheng, L., and Zachary, I. C. Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway. EMBO Rep, 9: 983-989, 2008. 4.Karmakar, S., Banik, N. L., and Ray, S. K. Curcumin suppressed anti-apoptotic signals and activated cysteine proteases for apoptosis in human malignant glioblastoma U87MG cells. Neurochem Res, 32: 2103-2113, 2007. 5.Karmakar, S., Banik, N. L., and Ray, S. K. Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice. Cancer, 112: 596-607, 2008. 6.Martinkova, E., Dontenwill, M., Frei, E., and Stiborova, M. Cytotoxicity of and DNA adduct formation by ellipticine in human U87MG glioblastoma cancer cells. Neuro Endocrinol Lett, 30 Suppl 1: 60-66, 2009. 7.Zhang, R., Banik, N. L., and Ray, S. K. Combination of all-trans retinoic acid and interferon-gamma upregulated p27(kip1) and down regulated CDK2 to cause cell cycle arrest leading to differentiation and apoptosis in human glioblastoma LN18 (PTEN-proficient) and U87MG (PTEN-deficient) cells. Cancer Chemother Pharmacol, 62: 407-416, 2008.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
Available
Description	Disease: Astrocytoma, glioblastoma Origin: Derived from a malignant glioma from a female patient by explant technique Species: Homo sapiens Tissue: Brain Morphology: Epithelial Properties: Adherent Cytogenic data: This is a hypodiploid human cell line Patient: Female, Caucasian, 44 yrs of age Medium: AddexBio-formulated EMEM (C0005-01) + 10% FBS Subculture: 1:2 to 1:5 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37 degree C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Isoenzymes: AK-1, 1 ES-D, 1 G6PD, B GLO-I, 1 Me-2, 1 PGM1, 2 PGM3, 1 DNA Profile (STR): Amelogenin: X CSF1PO: 10, 11 D13S317: 8, 11 D7S820: 8, 9 D5S818: 11, 12 D16S539: 12 vWA: 15, 17 THO1: 9.3 TPOX: 8 Citation Format: If use of this culture results in a scientific publication, it should be cited in the publication as: U87MG (AddexBio C0005002) Mutations in U87MG Cells Related cells by Organ: B103 LN-319 SH-Sy5y cells U87MG cells
Storage condition	LN2
Manufacturers Category	Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: One Frozen vial

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Delivery expected until 8/28/2025

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