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8505C cells

8505C cells

Item no.	C0025002
Manufacturer	Addexbio
Amount	One Frozen vial
Category	Oncology Cell Lines & Cell Culture Cell Lines By Organ Lung Cancer Bladder Cancer Thyroid Cancer
Type	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Ribeiro, F. R., Meireles, A. M., Rocha, A. S., and Teixeira, M. R. Conventional and molecular cytogenetics of human non-medullary thyroid carcinoma: characterization of eight cell line models and review of the literature on clinical samples. BMC Cancer, 8: 371, 2008. 2.Schweppe, R. E., Klopper, J. P., Korch, C., Pugazhenthi, U., Benezra, M., Knauf, J. A., Fagin, J. A., Marlow, L. A., Copland, J. A., Smallridge, R. C., and Haugen, B. R. Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. J Clin Endocrinol Metab, 93: 4331-4341, 2008. 3.Arlot-Bonnemains, Y., Baldini, E., Martin, B., Delcros, J. G., Toller, M., Curcio, F., Ambesi-Impiombato, F. S., D'Armiento, M., and Ulisse, S. Effects of the Aurora kinase inhibitor VX-680 on anaplastic thyroid cancer-derived cell lines. Endocr Relat Cancer, 15: 559-568, 2008. 4.Ito, T., Seyama, T., Hayashi, Y., Hayashi, T., Dohi, K., Mizuno, T., Iwamoto, K., Tsuyama, N., Nakamura, N., and Akiyama, M. Establishment of 2 human thyroid-carcinoma cell-lines (8305c, 8505c) bearing p53 gene-mutations. Int J Oncol, 4: 583-586, 1994. 5.Nucera, C., Nehs, M. A., Mekel, M., Zhang, X., Hodin, R., Lawler, J., Nose, V., and Parangi, S. A novel orthotopic mouse model of human anaplastic thyroid carcinoma. Thyroid, 19: 1077-1084, 2009. 6.Lin, S. F., Price, D. L., Chen, C. H., Brader, P., Li, S., Gonzalez, L., Zhang, Q., Yu, Y. A., Chen, N., Szalay, A. A., Fong, Y., and Wong, R. J. Oncolytic vaccinia virotherapy of anaplastic thyroid cancer in vivo. J Clin Endocrinol Metab, 93: 4403-4407, 2008. 7.Zhu, W., Ou, Y., Li, Y., Xiao, R., Shu, M., Zhou, Y., Xie, J., He, S., Qiu, P., and Yan, G. A small-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway. Mol Pharmacol, 75: 812-819, 2009.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
Available
Description	Disease: Thyroid carcinoma, undifferentiated Origin: Established from undifferentiated thyroid carcinomas Species: Homo sapiens Tissue: Thyroid gland Morphology: Epithelial Properties: Adherent Cytogenic data: Tumorigenic Patient: Female, 78 yrs of age Medium: RPMI1640 + 10% FBS Subculture: 1:3 to 1:4 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Protein Expression: cytokeratin +, cytokeratin-7 +, cytokeratin-8 +, cytokeratin-17 -, cytokeratin-18 +, cytokeratin-19 +, desmin -, endothel -, EpCAM +, GFAP -, HMB-45 -, neurofilament -, thyroglobulin -, vimentin + Mutations in 8505C Cells Related cells by Organ: 8505C cells FTC-238 cells K1 cells
Storage condition	LN2
Manufacturer - Category	Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: One Frozen vial

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