HEK-CaSR cells

Channel/Receptor:
CaSR, CaR
Background :
The calcium-sensing receptor (CaSR) is a G-protein coupled receptor which senses extracellular levels of calcium ion. In the parathyroid gland, the calcium-sensing receptor controls calcium homeostasis by regulating the release of parathyroid hormone (PTH). In colorectal cancer, CaSR has been downregulated while it has been upregulated in breast cancer.
Expression System :
HEK293 cells, Embryonic Kidney Epithelial Cells
Growth Condition :
Details enclosed in shipping Information Sheet
Subculture :
1:2 to 1:3 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C
Morphology and Properties :
Adherent epithelium
Gene Name :
CaSR, CaR
Sequence :
GenBank accession number AY214122
Packaging :
Cryopreserved cells, 1 x 10⁶ cells/vial
Freezing Medium:
Complete culture medium supplemented with 5% (v/v) DMSO
Storage Recommendation :
Vapor phase of liquid nitrogen
Biosafety Level:
I
Sterility:
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
Pathogens:
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
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