Osteoclast cells (human)

PMC

Osteoclast cells (human) are bone marrow mononuclear cell-derived osteoclast precursor cells (1.5x106cells/vial). For guaranteed optimal recovery and differentiation we recommend Osteoclast Wash Medium (PMC-OSCMW) and CSF/RANKL-containing Osteoclast Culture Medium (for human) (PMC-OSCMHB). Together, these products are useful for studies of osteoclast formation, bone resorption, osteoporosis, rheumatoid arthritis, Paget' s disease and others.
Bone mass is controlled by the dynamic interplay of bone-forming osteoblasts and bone-degrading osteoclasts. In recent years, a system has been established that induces bone marrow cells to differentiate into osteoclasts using M-CSF (Macrophage Colony Stimulating Factor) and RANKL (Receptor Activator of NF kappa B Ligand).
Osteoclast cells (human) are bone marrow mononuclear cell-derived osteoclast precursor cells (1.5x106cells/vial). Upon receipt of dry ice-packaged shipment directly from Japan, either immediately store in liquid nitrogen or introduce cells directly into culture. Biosafety level 2 containment precautions should be used when handling this product. For guaranteed optimal recovery and differentiation we recommend Osteoclast Wash Medium (PMC-OSCMW) and CSF/RANKL-containing Osteoclast Culture Medium (for human) (PMC-OSCMHB). Together, these products are useful for studies of osteoclast formation, bone resorption, osteoporosis, rheumatoid arthritis, Paget' s disease and others.
Product Warranty
When cells have been properly stored in liquid nitrogen and cultured according to instructions using recommended media and reagents, we guarantee against poor growth at the initiation of culture. For product support, please contact us (email: primarycell@cosmobio.co.jp). The warranty period is [within 6 months after receiving the product]. Warranty is not applicable if changes are made to the media or its usage, or if refrozen cells are utilized.