Comparison

Imiquimod

Item no. CD0115-100
Manufacturer Chemdea
Amount 100 mg
Category
Type Inhibitors
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias TLR7 activator and angiogenesis inhibitor
Available
Inhibitor Function
Toll-like Receptor 7 Ligand
Description
An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Reported to bind to the cell surface receptor, TLR7 (toll-like receptor 7), and induce the secretion of several pro-inflammatory cytokines and chemokines both in vitro and in vivo. See also Gardiquimod (Cat# CD0204).
Purity
99% by HPLC.
CAS #
99011-02-6
Solubility
DMSO (3 mg/mL), warming to 60C is required for complete solubilization.
Molecular Formula
C14H16N4
Molecular Weight
240.3
Notes
White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS.
Reference
1. Majewski, S., et al. Int. J. Dermatol. 2005, 44, 14

2. Gibson, S .J., et al. Cell. Immunol. 2002, 218, 74

3. Hemmi, H., et al. Nat. Immunol. 2002, 3, 196

4. Megyeri, K., et al. Mol. Cell. Biol. 1995, 15, 2207.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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