Anti Canine T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) mAb (Clone 1B9-7-1-1)

Research Area/Immunology & Inflammation/T Cell Receptors/Primary Antibodies; Research Area/Immunology & Inflammation/Adaptive Immunity/Primary Antibodies; Antibodies/T Cell Receptors/Primary Antibodies; Research Area/Cell Biology/Signal Transduction/Primary Antibodies; Antibodies/Primary Antibodies/T Cell Receptors; Research Area/Cell Types/T Cells/Primary Antibodies; Research Area/Development/Hematopoiesis/Primary Antibodies

Background
The CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.[7] [from: Wikipedia contributors. (2018, October 25). T-cell surface glycoprotein CD3 epsilon chain. In Wikipedia, The Free Encyclopedia. Retrieved 21:31, June 3, 2019]
Intended use
Optimal dilutions/concentrations should be determined by the end user. Not tested by IHC.
Antigen/Source
CD3ε
Host
Mouse
Immunogen
Canine
Reacts with
Canine
Not Reacts with
Feline
Clone
1B9-7-1-1
Isotype
IgG1
Fraction
Affinity Purified
Applications
Western Blot
Preservative
0.09% NaN3 in LIQ
Other
[Cross reactivity] Canine (Do not react with feline)
Storage
4C DNF

Monoclonal