Anti Myc Proto-Oncogene Protein (c-Myc) mAb (Clone 9E10)

Antibodies/Gene Expression & Transcription/Primary Antibodies; Antibodies/Primary Antibodies/Gene Expression & Transcription; Research Area/Cell Biology/Amino acid transport/Primary Antibodies; Research Area/Cell Biology/Apoptosis/Primary Antibodies; Research Area/Cell Biology/Cell Adhesion & Migration/Primary Antibodies; Research Area/Cell Biology/Cell Cycle/Primary Antibodies; Research Area/Cell Biology/Cell Growth/Primary Antibodies; Research Area/Cell Biology/Cell Proliferation/Primary Antibodies; Research Area/Cell Biology/Chromatin Assembly & Remodeling/Primary Antibodies; Research Area/Cell Biology/DNA Damage & Repair/Primary Antibodies; Research Area/Cell Biology/DNA Methylation/Primary Antibodies; Research Area/Cell Biology/DNA Replication/Primary Antibodies; Research Area/Cell Biology/Gene Expression & Transcription/Primary Antibodies; Research Area/Glycobiology/Glycolysis/Primary Antibodies; Research Area/Cell Biology/Hypoxic Metabolic & ER Stress/Primary Antibodies; Research Area/Cell Biology/Iron Homeostasis/Primary Antibodies; Research Area/Cell Biology/Mitosis/Primary Antibodies; Research Area/Cell Biology/Signal Transduction/Primary Antibodies; Research Area/Cell Biology/UV Induced DNA Damage/Primary Antibodies; Research Area/Cell Biology/Vesicular Biogenesis & Trafficking/Primary Antibodies; Research Area/Cell Types/Epithelial Cells/Primary Antibodies; Research Area/Cell Types/Fibroblasts/Primary Antibodies; Research Area/Cell Types/Glial Cells/Primary Antibodies; Research Area/Cell Types/Mesenchymal Stem Cells/Primary Antibodies; Research Area/Cell Types/Muscle Cells/Primary Antibodies; Research Area/Development/Brain & CNS/Primary Antibodies; Research Area/Development/Embryonic & Fetal Development/Primary Antibodies; Research Area/Development/Kidney/Primary Antibodies; Research Area/Development/Ovarian Follicle/Primary Antibodies; Research Area/Development/Urogenital System/Primary Antibodies; Research Area/Development/Wound Healing/Primary Antibodies; Research Area/Disease/Burkitt lymphoma/Primary Antibodies; Research Area/Oncology/Proto-oncogenes/Primary Antibodies; Research Area/Organelles & Subcellular Structures/Mitochondria/Primary Antibodies; Research Area/Organelles & Subcellular Structures/Telomeres/Primary Antibodies; Research Area/Organs & Organ Systems/Liver/Primary Antibodies; Research Area/Cell Biology/Oxygen transport/Primary Antibodies; Epigenetics/Antibodies/Chromatin IP

CAC

c-Myc is a very potent oncogene upregulated in various types of cancer. c-Myc, through its role as a transcription factor, alters the expression of hundreds of target genes, often oncogenes or tumor suppressors. Clone 9E10 recognizes recombinant proteins that incorporate the c-Myc epitope tag and detects human c-Myc proteins and peptides in random coil rather than alpha-helix structures.
References:
1) Mateos-Gomez et al. 2015. Nature. 518(7538):254-7. PMID: 25642960. (WB)
2) Zhang et al. 2014. Genes Dev. 28(8):829-34. PMID: 24736842. (ChIP)
3) Zhou et al. 2012. J Cell Biol. 196(2):203-11. PMID: 22270916. (IP, WB)
4) Mendes et al. 2010. J Biol Chem. 285(50):39117-26. PMID: 20937822. (IP, WB)
5) Royds et al. 1992. J Pathol. 166(3):225-33. PMID: 1381423. (IHC)
6) Spandidos et al. 1987. Anticancer Res. 7(6):1299-304. PMID: 3327455. (IHC)
7) Kari et al. 1986. J Virol. 60(2):345-52. PMID: 3021969. (IP)
8) Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782. (WB)

Monoclonal