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Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (a. a. 155), Polypeptide

Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (a. a. 155), Polypeptide

Item no.	DAG290
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Peptides By Organ Colorectal Cancer Heart & Blood Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	>95%pure (SDS-PAGE and HPLC analysis). Purified using chromatographic techniques.Product is sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FL,FLT3L,fms-related tyrosine kinase 3 ligand,flt3 ligand,FLT3LG,SL cytokine
Available
Manufacturer - Applications	The ED50, calculated by the dose-dependent stimulation of the proliferation of humanOCMI-AML5 cells is 0.5 to 1.0ng/ml. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should not necessarilybe excluded.
Storage Conditions	Thelyophilized product, though stable for 3 weeks at room temperature, is beststored at –20C. After reconstitution, short term (up to 1 week) store at2-8oC. Long-term, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoidmultiple freeze/thaw cycles.
Full name	Fms-Related Tyrosine Kinase 3 Ligand
Product Overview	RecombinantHuman FLT3LG is asingle, non-glycosylated, polypeptide chain containing 155 amino acids andhaving a molecular mass of 17, 605Da, the sequence of the first fiveN-terminal amino acids was determined and was found to beThr-Gln-Asp-Cys-Ser. Contains less than 1% dimers and aggregates.
Abbr	FLT3LG (a.a. 155)
Manufacturer - Format	Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration of> 100ug/ml. Further dilutions can be made in other aqueous buffers.
Buffer	Not applicable
Concentration	Not applicable
Preservative	None
Gene Information - Gene Name	FLT3LGfms-related tyrosine kinase 3 ligand [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_001204502
Gene Information - Protein Refseq	NP_001191431
Gene Information - MIM	600007
Gene Information - Pathway	Cytokine-cytokinereceptor interaction, Hematopoietic cell lineage, Pathways in cancer
Gene Information - Function	cytokine activity, receptor binding
Antigen Description	Fms-related tyrosine kinase 3 ligand (FLT3LG) isa protein which in humans is encoded by the FLT3LG gene. Flt3 ligand (FL) isa hematopoietic four helical bundle cytokine. It is structurally homologousto stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergywith other growth factors, Flt3 ligand stimulates the proliferation anddifferentiation of various blood cell progenitors.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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