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Recombinant Mouse Colony Stimulating Factor 2 Polypeptide (a. a. 128)

Recombinant Mouse Colony Stimulating Factor 2 Polypeptide (a. a. 128)

Item no.	DAG340
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology Peptides & Proteins Peptides By Organ Heart & Blood Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	>98% pure (HPLC, FPLC and reducing and non-reducingSDS-PAGE). Endotoxin level is less than 0.1ng/ug (IEU/ug). Purified bychromatographic techniques. Product is sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Csf2,colony stimulating factor 2 (granulocyte-macrophage),Granulocyte MacrophageColony Stimulating Factor,Csfgm,Gm-CSf,MGI-IGM,MGC151255,MGC151257,put.GM-CSF,OTTMUSP00000005830,colony-stimulating factor
Available
Manufacturer - Applications	The ED50 as determined by the dose-dependent stimulationof the proliferation of mouse FDC-P1 cell line is <0.2ng/ml, correspondingto a specific activity of 5 x 106 IU/mg. Each laboratory should determine anoptimum working titer for use in its particular application. Otherapplications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions	The lyophilized product, though stable for 3 weeks at roomtemperature, is best stored at –20°C. After reconstitution, short term (up to1 week) store at 2-8oC. Long term, add 0.1% HSA or BSA, aliquot and store at–20°C. Avoid multiple freeze/thaw cycles.
Full name	Colony Stimulating Factor 2 (Granulocyte-macrophage)
Product Overview	Recombinant mouse Csf2 is a single non-glycosylated polypeptidechain containing 125 amino acids and having a molecular weight of 14, 285.35Da, was expressed in E. coli. The sequence of the first five N-terminal aminoacids was determined to be Met-Ala-Pro-Thr-Arg. Contains less than 1% dimersand aggregates.
Abbr	Csf2
Manufacturer - Format	Purified, Lyophilized Reconstitute using sterile deionized waterto a concentration >100ug/ml. Further dilutions can be made inother aqueous buffers.
Buffer	Lyophilizedfrom 2mM Sodium phosphate buffer, pH 7.4 + 0.1
Concentration	1mg/ml(OD280nm, E0.1% = 0.765) (prior to lyophilization)
Preservative	None
Gene Information - mRNA Refseq	NM_009969
Gene Information - Protein Refseq	NP_034099
Gene Information - Pathway	Amoebiasis, Cytokine Signaling in Immune system, Cytokine-cytokine receptor interaction, Cytokines and Inflammatory Response (BioCarta), Fc epsilon RI signalingpathway, HTLV-I infection, Hematopoietic cell lineage, Immune System, Interleukin-2 signaling, Jak-STAT signaling pathway, Natural killer cellmediated cytotoxicity, Rheumatoid arthritis, Salmonella infection, T cellreceptor signaling pathway
Gene Information - Function	cytokineactivity, granulocyte macrophage colony-stimulating factor receptor binding, growth factor activity
Antigen Description	GM-CSFstimulates stem cells to produce granulocytes (neutrophils, eosinophils, andbasophils) and monocytes. Monocytes exit the circulation and migrate intotissue, whereupon they mature into macrophages and dendritic cells. Thus, itis part of the immune/inflammatory cascade, by which activation of a smallnumber of macrophages can rapidly lead to an increase in their numbers, aprocess crucial for fighting infection. The active form of the protein isfound extracellularly as a homodimer.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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