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Recombinant Human Oncostatin M (a. a. 227)

Recombinant Human Oncostatin M (a. a. 227)

Item no.	DAG305
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity By Organ Heart & Blood Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	>98%pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE). Endotoxin level isless than 0.1ng/ug (IEU/ug). Purified by chromatographic techniques. Productis sterile filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	OSM,oncostatin M, MGC20461, oncostatin-M, OTTHUMP00000198700, ONCM_HUMAN,Oncostatin M, Oncostatin-M
Available
Manufacturer - Applications	The ED50 asdetermined by dose-dependent stimulation of human TF-1 cells is <2ng/mlcorresponding to a specific activity of 5 x 105 IU/mg. Eachlaboratory should determine an optimum working titer for use in itsparticular application. Other applications have not been tested but use insuch assays should not necessarily beexcluded.
Storage Conditions	The lyophilizedproduct, though stable for 3 weeks at room temperature, is best stored at–20°C. After reconstitution, short term (up to 1 week) store at 2-8oC. Longterm, add 0.1% HSA or BSA, aliquot and store at –20°C. Avoid multiplefreeze/thaw cycles.
Full name	Oncostatin M
Product Overview	RecombinantHuman Oncostatin M is a single, non-glycosylated, polypeptide chaincontaining 227 amino acids and having a molecular weight of 26 kDa, wasexpressed in E. coli. The sequence of the first five N-terminal amino acidswas determined to be Met-Ala-Ala-Ile-Gly. Contains less than 1% dimers andaggregates.
Abbr	OSM (a.a. 227)
Manufacturer - Format	Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration >100ug/ml.Further dilutions can be made in other aqueous buffers.
Buffer	Not applicable
Concentration	1mg/ml(OD280nm, E0.1% = 0.45) (prior to lyophilization)
Preservative	None
Gene Information - Gene Name	OSMoncostatin M [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_020530
Gene Information - Protein Refseq	NP_065391
Gene Information - MIM	165095
Gene Information - Pathway	Adipogenesis, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Gene Information - Function	cytokine activity, growth factor activity, oncostatin-M receptor binding
Antigen Description	Oncostatin M, also known as OSM, is aprotein that in humans is encoded by the OSM gene. OSM is a pleiotropiccytokine that belongs to the interleukin 6 group of cytokines. Of thesecytokines it most closely resembles leukemia inhibitory factor (LIF) in bothstructure and function. However, it is as yet poorly defined and is provingimportant in liver development, haematopoeisis, inflammation and possibly CNSdevelopment. It is also associated with bone formation and destruction.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 10/9/2025

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