Recombinant Herpes Simplex Virus-2, Glycoprotein G (a.a.525-578), His-tagged

Suitable for use in ELISA and Western blot. Each, laboratory should determine an optimum working titer for use in its, particular application. Other applications have not been tested but use in, such assays should not necessarily be excluded.

Herpes Simplex Virus Glycoprotein G

Herpes, simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1, and 2 (HHV-1 and -2), are two members of the herpes virus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold, sores) and HSV-2 (which produces most genital herpes) are ubiquitous and, contagious. They can be spread when an infected person is producing and shedding, the virus. Symptoms of herpes simplex virus infection include watery blisters, in the skin or mucous membranes of the mouth, lips or genitals. Lesions heal, with a scab characteristic of herpetic disease. Sometimes, the viruses cause, very mild or atypical symptoms during outbreaks. However, as neurotropic and, neuroinvasive viruses, HSV-1 and -2 persist in the body by becoming latent, and hiding from the immune system in the cell bodies of nerves. After the, initial or primary infection, some infected people experience sporadic, episodes of viral reactivation or outbreaks. In an outbreak, the virus in a, nerve cell becomes active and is transported via the nerve"s axon to the, skin, where virus replication and shedding occur and cause new sores.

HSV-2 gG (a.a 525-578), His-tagged

20mM Tris-HCl, pH 7.6 containing 150mM Sodium, chloride, 1mM EDTA

None