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Profilin 1 (recombinant human)

Profilin 1 (recombinant human)

Item no.	PR01-A
Manufacturer	Cytoskeleton
Amount	1 x 50 ug
Category	Neuroscience Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cytoskeleton Cell Migration & Invasion Microfilaments
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
Citations	Moseley, J. B., Sagot, I., Manning, A. L., Xu, Y., Eck, M. J., Pellman, D. and Goode, B. L. (2004). A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol. Biol. Cell 15, 896-907. Vignjevic, D., Yarar, D., Welch, M. D., Peloquin, J., Svitkina, T. and Borisy, G. G. (2003). Formation of filopodia-like bundles in vitro from a dendritic network. J. Cell Biol. 160, 951-962.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Actin, Actin Binding Protein, Profilin protein, profilin, actin polymerization
Similar products	Actin, profilin, Actin Binding Protein, actin polymerization, Profilin protein
Available
Shipping Temperature	AT
Storage Conditions	On Arrival: 4°C Lyophilized Protease Inhibitor Cocktail is stable at 4C desiccated (<10% humidity) for 1 year. Each tube of Protease Inhibitor Cocktail should be resuspended in 1ml of DMSO (dimethyl sulfoxide) to give a 100X strength stock. The reconstituted stock can be stored at 4C for up to 6 months or at -70C for up to 1 year.
Associated Products	This protease inhibitor cocktail is used in the following Cytoskeleton Activation Assays: Ras activation assay Biochem kit (Cat. # BK008) Cdc42 activation assay Biochem kit (Cat. # BK034) Rac activation assay Biochem kit (Cat. # BK035) RhoA activation assay Biochem kit (Cat. # BK036) G-actin : F-actin in vivo assay Biochem kit (Cat. # BK037) Microtubule : tubulin in vivo assay Biochem kit (Cat. # BK038) RhoA G-LISA Activation Assay Kit (luminescence) (Cat. #BK121) RhoA G-LISA Activation Assay Kit (colorimetric) (Cat. # BK124) Rac1, 2, 3 G-LISA Activation Assay Kit (colorimetric) (Cat. #BK125) Rac1 G-LISA Activation Assay Kit (luminescence) (Cat. # BK126) Cdc42 G-LISA Activation Assay (Cat. # BK127>) Rac1 G-LISA Activation Assay (Colorimetric Based) (Cat. # BK128) RalA G-LISA Activation Assay (Colorimetric Based) (Cat. # BK129)
Delivery Time	1-2 Weeks
Product Uses	Inhibition of a wide range of proteases. Popular Activation Assay Component
Material	Protease Inhibitor Cocktail is supplied as a white lyophilized powder. The cocktail contains the following protease inhibitors, Pepstatin A, Leupeptin, Benzamidine, Na-p-tosyl-L-arginine methyl ester (TAME). At 1X final working concentration the inhibitors are at 1 uM, 1.5 uM, 1 mM and 0.4 mM respectively.
Mode of Action	pepstatin A Reversibly inhibits some aspartic proteases Leupeptin Reversibly inhibits trypsin like serine and some cysteine proteases Benzamidine Inhibits serine proteases TAME Inhibits arginine proteases, a thrombin and trypsin inhibitor

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

PR01-A.pdf

PR01-A-datasheet.pdf

PR01-A-safety-datasheet.pdf