Murine IL-31 Pre-Coated ELISA Kit

IL-31 is a T cell-derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (also known as gp130-like receptor or IL-31RA) and Oncostatin-M receptor (OSMR). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, JAK1, and JAK2 signaling pathways. IL-31-regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.



The BioGems Murine IL-31 Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure IL-31 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for IL-31. It contains E. coli-expressed recombinant IL-31. The detection antibody is a biotinylated goat polyclonal antibody specific for IL-31. The kit is analytically validated with ready to use reagents.