Galectin-3 ELISA Kit, Human

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human Galectin-3. The Human Galectin-3 is for research use only. Not for diagnostic or therapeutic procedures. Galectin-3 is a protein that belongs to the lectin family, it is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. Galectin-3 has an affinity for beta-galactosides and exhibits antimicrobial activity against bacteria and fungi. It is involved in many biological processes: cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cell cycle, and apoptosis. Given galectin-3’s broad biological functionality, it has been demonstrated to be involved in cancer, inflammation and fibrosis, heart disease, and stroke. A correlation between galectin-3 expression levels and various types of fibrosis has been found. Galectin-3 is upregulated in cases of liver fibrosis, renal fibrosis, and idiopathic pulmonary fibrosis (IPF). Elevated levels of galectin-3 have been found to be significantly associated with higher risk of death in both acute decompensated heart failure and chronic heart failure populations. Also, galectin-3 has been suggested to play important roles in cancer metastasis.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

2.46 pg/ml

85 % - 105 %

2.7 - 13.1 ng/ml

1.7 % - 3.5 %