IGF-1R / CD221 ELISA Kit, Human

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IGF-1R. The Human IGF-1R/CD221 ELISA is for research use only. Not for diagnostic or therapeutic procedures. The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone called insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. IGF-1 plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscle and other target tissues. Mice lacking the IGF-1 receptor die late in development, and show a dramatic reduction in body mass, testifying to the strong growth-promoting effect of this receptor. Studies showed that the IGF-1R is implicated in several cancers, including breast, prostate, and lung cancers.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

13.27 pg/ml

73 % - 113%

n.d. - 1.6 ng/ml

5.7 % - 9.7 %