Apolipoprotein H / Apo H ELISA Kit, Human

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human Apo H. The Human Apolipoprotein H/Apo H ELISA is for research use only. Not for diagnostic or therapeutic procedures. Apolipoprotein H (Apo H), previously known as beta2-glycoprotein I, is a multifunctional apolipoprotein that in humans is encoded by the APOH gene. It is a glycoprotein synthesized by liver cells. One of its functions is to bind cardiolipin. Apo H binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. Apo H has a complex involvement in agglutination, it appears to alter ADP mediated agglutination of platelets. It may prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. Normally Apo H assumes an anti-coagulation activity in serum (by inhibiting coagulation factors). Its plasma concentrations are strongly associated to metabolic syndrome alterations and vascular disease in type 2 diabetic and could be considered as a clinical marker of cardiovascular risk.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

16.18 pg/ml

4.6 - 54.7 ug/ml

2.4 % - 6.3 %