MMP-9 ELISA Kit, Human

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human MMP-9. The Human MMP-9 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is a matrixin, a class of enzymes that belong to the zinc-metalloproteinases family involved in the degradation of the extracellular matrix. In humans the MMP9 gene encodes for a signal peptide, a propeptide, a catalytic domain with inserted three repeats of fibronectin type II domain followed by a C-terminal hemopexin-like domain. Thrombospondins, intervertebral disc proteins, regulate the effective levels of MMP-2 and -9, which are key effectors of ECM remodeling. MMP-9 has been found to be associated with numerous pathological processes, including cancer, immunologic and cardiovascular diseases. This kit is designed to measure MMP-9 (92 kDa pro- and 82 kDa active forms but not the 65 kDa form).

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

1.70 pg/ml

85 % - 108 %

262.35 - 26252.04 ng/ml

3.9 % - 5.7 %