CCL5 / RANTES ELISA Kit, Mouse

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse RANTES. The Mouse CCL5/RANTES ELISA is for research use only. Not for diagnostic or therapeutic procedures. Chemokine (C-C motif) ligand 5 (CCL5) also known as RANTES, is a chemotactic cytokine. It is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines (i.e., IL-2 and IFN-gamma) that are released by T cells, CCL5 also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. It is also an HIV-suppressive factor released from CD8+ T cells. Recently, the RANTES protein has been engineered for in vivo production by Lactobacillus bacteria, and this solution is being developed into a possible HIV entry-inhibiting topical microbicide.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

0.12 pg/ml

80 % - 113 %

n.d. - 77.5 pg/ml

2.6 % - 3.9 %