Rat TGF-beta1 ELISA Kit

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat TGF-beta1. The Rat TGF-beta1 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Transforming growth factor beta 1 (TGF-beta1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. TGF-betas are a multifunctional set peptides that controlsproliferation, differentiation, and other functions in many cell types. TGF-betas act synergistically with TGFA in inducingtransformation. It also acts as a negative autocrine growth factor. Dysregulation of TGF-beta activation and signaling may result in apoptosis. Many cells synthesize TGF-beta and almost all of them have specific receptors for this peptide. TGF-beta1, TGF-beta2 , and TGF-beta3 all function through the same receptor signaling systems. TGF-beta1 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Most immune cells (orleukocytes) secrete TGF-beta1. TGF-beta1 is related to cancer, autoimmune diseases, liver diseases, kidney diseases, diabetes, cardiovascular diseases, asthma, chronic obstructive pulmonary disorder (COPD), cystic fibrosis (CF) and so on.

Sandwich ELISA

serum, plasma, cell culture supernates

4C (unopened)
standard stored at -20C, others stored at 4C (opened)

3.36 pg/ml

83 % - 117 %

28689.6 - 98954.0 pg/ml

2.0 % - 5.3 %