sAPPbeta ELISA Kits (human, mouse, rat, rabbit)

Manufacturer Fivephoton
Category Products / ELISA
Type Elisa-Kit
Specific against Mouse, Rat, Rabbit
Amount 96T
ArtNr sAPPbeta-ELISA
Eclass 6.1 32160605
Eclass 9.0 32160605
Available
Poisonous Material
Sodium Azide (0.1%)
Highlights
Fully pre-configured sandwich ELISA format providing convenience, high sensitivity and selectivity.
Strip plate configuration allowing separate use and storage of sections of the ELISA plate.
Affinity purified polyclonal capture antibody on plate. Separate HRP-conjugated detection antibody. Provided as a complete, pre-configured kit.
High sensitivity detection of sAPPß in cell culture medium and biological fluids. Assay ranges 0.5-60pg/ml depending on species. Detects the soluble beta-secretase cleavage product of amyloid precursor protein in cell culture medium and biological fluids after sedimentation of cells. Assays are done in the supernatant fraction to quantitate sAPPß.
This ELISA kit also detects full length APP in cell and tissue lysates after detergent solubilization from the membrane. To distinguish sAPPß from membrane bound APP, use the sample preparation method noted above (i.e. collect and assay the supernatant fraction without membrane solubilization).
Rapid assay with colorimetric detection (measure reaction at 450nm). Total incubation of sample with ELISA plate and HRP detection antibody is 1 hr at 37C or 2 hr at RT.
Background
sAPPbeta is the extracellular soluble fragment of amyloid precursor protein (APP) cleaved by beta-secretase into a 654 amino acid peptide. Cleavage of APP by beta-secretase in the extracellular domain is the first cleavage processing step generating amyloid-beta peptide. Membrane embedded gama-secretase subsequently cleaves APP within the transmembrane domain and generates amyloid-beta peptide of variable length.1 This sAPP beta ELISA detects the sAPP beta peptide in cell culture medium and biological fluids, including CSF.
Amount: 96T
Available: In stock
Listprice: €771.44
Discount: -10%
Price: €694.30
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