TIM3

Manufacturer	GenomeMe
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies Primary Antibodies By Organ Lung Cancer
Type	Antibody Monoclonal
Specific against	Human
Clone	IHC003
Amount	0.1ml
Host	Mouse
Item no.	GME-IHC003-100
eClass 6.1	32160702
eClass 9.0	42030590
Available
Description	T-cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.
CE	CE, IVD
Positive Control	Tonsil
Source	Mouse Monoclonal
Dilution Range	1:100 - 1:200
References	Monney L, et al. Nature. 2002; 415:536-41. Sanchez-Fueyo A, et al. Nat Immunol. 2003; 4:1093-101. Anderson AC. Cancer Immun Res. 2014; 2:393–8. Gao X, et al. PLoS One. 2012; 7:e30676.

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GME-IHC003-100-safety-datasheet.pdf