Calbindin Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-Calbindin Polyclonal Antibody detects human calbindin protein. Sequence homology predicts that it will also to react with mouse and rat calbindin.

Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27 kD protein induced by vitamin D in the duodenums of young birds. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains four active calcium-binding domains and two modified domains that presumably have lost their calcium-binding capacity. The neurons in the brains of patients with Huntington’s disease are calbindin-depleted. GenScript, Rabbit Anti-Calbindin Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide from residues 150-200 of human calbindin protein (Swiss Prot: P05937).

Immunoaffinity chromatography

Small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.