BMP-7 Antibody (1G10H5), mAb, Mouse

USA

React with Human BMP-7, not cross-react with BMP-14

BMP-7, or osteogenic protein 1 (OP-1), is one of at least 15 structurally and functionally related BMPs, all members of the transforming growth factor beta (TGF-beta) superfamily. BMPs regulate cartilage and bone formation, embryogenesis and morphogenesis of various tissues and organs, and the growth, differentiation, chemotaxis and apoptosis of various cell types. Biologically active BMP-7 is a disulfide-linked homodimer. Cellular responses to BMP-7 have been shown to be mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. GenScript, Human BMP-7 Antibody (1G10H5), mAb, Mouse, is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified human recombinant BMP-7 protein (Swiss Prot: P18075).

Purified human recombinant BMP-7 protein (Swiss Prot: P18075)

Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.