IP-10 Antibody (1G12E6), mAb, Mouse

USA

GenScript, IP10 Antibody, mAb, Mouse, detects human IP10

Interferon-gamma-inducible 10 kD protein (IP10) is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells, and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis, and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP10 to regulate angiogenic activity in cancer and in idiopathic pulmonary fibrosis. GenScript, IP10 Antibody, mAb, Mouse, is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified recombinant human protein IP10 (Swiss-Prot P02778).

Purified recombinant human protein IP10 (Swiss-Prot: P02778)

Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.