Phosphotyrosine Antibody (18E10), mAb, Mouse

USA

-20°C

Phosphotyrosine is a tyrosine residue covalently bound to a phosphate via its hydroxyl group. A tyrosine kinase catalyzes the transfer of a phosphate from ATP to a tyrosine residue on the protein substrate. Tyrosine phosphorylation plays a key role in intracellular and cancer development. Many tyrosine kinases are l drug targets for different forms of cancer. Phosphotyrosine antibody specifically binds tophosphotyrosine residues. It is a valuablel tool to analyze tyrosine phosphorylation and monitor the activity of tyrosine kinase in high throughput drug discovery.
GenScript Phosphotyrosine Antibody (18E10), mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0-Ag14 myeloma and B-lymphocytes harvested from mouse immunized with phosphotyrosine containing carrier protein.