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CHO-K1/CRF1/Gα15 Stable Cell Line

CHO-K1/CRF1/Gα15 Stable Cell Line

Item no.	M00343
Manufacturer	GenScript
Amount	2 vials
Category	Metabolism Glucose Homeostasis Cell Lines & Cell Culture Cell Lines
Type	Cell line
Specific against	other
Dry ice	Yes
ECLASS 10.1	42040401
ECLASS 11.0	42040401
UNSPSC	41106509
Alias	molecule/M00343-CRF1,
Similar products	CHO-K1/CRF1/Galpha15
Shipping Condition	Dry ice
Available
Manufacturer - Category	Cellular Analysis
Country of Origin	USA
Shipping Temperature	-80°C
Storage Conditions	-196°C
Product Line	GPCR Cell Lines
Manufacturer - portfolio	Cell Line (CPBU)
Description	The CRF1 receptor is a Gs-coupled GPCR expressed in the brain and pituitary gland that binds to several neuropeptides, including corticotropin-releasing factor (CRF) and urocortin, and the amphibian peptide sauvagine. CRF plays a predominant role in stress response mediated by the hypothalamic-pituitary-adrenal axis, and alterations in CRF and its receptors CRF1 and CRF2 appear to be linked to depression and anxiety. In comparison to the CRF2 receptor, the CRF1 receptor has received considerable attention as a potential therapeutic target for the treatment of stress-related disorders such as adrenocorticotropin hypersecretion, increased colonic motility and exaggerated fear and anxiety-related behavior.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.