Comparison

CHO-K1/DP1/Gα15 Stable Cell Line European Partner

Item no. M00453
Manufacturer GenScript
Amount 2 vials
Category
Type Cell line
Specific against other
Dry ice Yes
ECLASS 10.1 42040401
ECLASS 11.0 42040401
UNSPSC 41106509
Alias molecule/M00453-DP1,
Similar products CHO-K1/DP1/Galpha15
Shipping Condition Dry ice
Available
Manufacturer - Category
Cellular Analysis
Country of Origin
USA
Shipping Temperature
-80°C
Storage Conditions
-196°C
Product Line
GPCR Cell Lines
Manufacturer - portfolio
Cell Line (CPBU)
Description
DP1 is a Gs-coupled GPCR expressed in the colon, eye, platelets, eosinophils, that bind to PGD2 and PGE2. DP1 can inhibit platelet aggregation, and also inhibit leukotriene B4 and superoxide anion (O2-) release from human neutrophils. It can relax smooth muscle and regulate eosinophil apoptosis. DP receptor knockout OVA-challenged mice exhibit reduced Th2 cytokine levels and lymphocyte accumulation in the lung. In addition, they failed to produce asthmatic responses.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2 vials
Available: In stock
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