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CHO-K1/CysLT1/Gα15 Stable Cell Line

CHO-K1/CysLT1/Gα15 Stable Cell Line

Item no.	M00462
Manufacturer	GenScript
Amount	2 vials
Category	Oncology Cell Lines & Cell Culture Cell Lines By Organ Lung Cancer Skin Cancer
Type	Cell line
Specific against	other
Dry ice	Yes
ECLASS 10.1	42040401
ECLASS 11.0	42040401
UNSPSC	41106509
Alias	molecule/M00462-CysLT1,
Similar products	CHO-K1/CysLT1/Galpha15
Shipping Condition	Dry ice
Available
Manufacturer - Category	Cellular Analysis
Country of Origin	USA
Shipping Temperature	-80°C
Storage Conditions	-196°C
Product Line	GPCR Cell Lines
Manufacturer - portfolio	Cell Line (CPBU)
Description	CysLT1 (Cysteinyl leukotriene receptor 1) is previous named as LTD4 receptor (leukotriene D4 receptor). It is a receptor for cysteinyl leukotrienes and has highest affinity to leukotriene D4 (LTD4). The receptor mediates contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung caused by LTD4. A CysLT1 selective antagonist, montelukast, is used clinically in the treatment of asthma.. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.