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Urotensin II, human

Urotensin II, human

Item no.	RP10096-0.5
Manufacturer	GenScript
Amount	0.5 mg
Category	Peptides & Proteins Cardiovascular Research Atherosclerosis Hypertension Peptides
Type	Peptides
Specific against	Human (Homo sapiens)
Purity	> 95%
Sequence	ETPDCFWKYCV ; {GLU}{THR}{PRO}{ASP}{CYS}{PHE}{TRP}{LYS}{TYR}{CYS}{VAL}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP10096-Urotensin_II_U_II_human, The orphan receptor GPR14 has been found to be expressed predominantly in cardiovascular tissue and many serve as a receptor for urotensin II (human). Urotensin II (human) binds with high affinity to recombinant GPR14. It is found within both vascular and cardiac tissue. Urotensin II vasoconstrictive potency is reported to be an order of magnitude greater than that of endothelin-1 (ET-1), which would make it the most potent mammalian vasoconstrictor identified to date. Recently, our research data has shown that urotensin II is involved in the development of rat cardiac hypertrophy: Contractile response to human U II in rat and human pulmonary arteries was increased by endothelial factors, vascular tone, and the onset of pulmonary hypertension. </td></tr><tr><th>Solubility</th><td colspan="7"> The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Before use, store the peptide in the DRY form at 0C - 5C. For best and most repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions. </td></tr>
Similar products	Urotensin
Available
Country of Origin	USA
Storage Conditions	Before use, store the peptide in the DRY form at 0C - 5C. For best and most repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions.
Description	The orphan receptor GPR14 has been found to be expressed predominantly in cardiovascular tissue and many serve as a receptor for urotensin II (human). Urotensin II (human) binds with high affinity to recombinant GPR14. It is found within both vascular and cardiac tissue. Urotensin II vasoconstrictive potency is reported to be an order of magnitude greater than that of endothelin-1 (ET-1), which would make it the most potent mammalian vasoconstrictor identified to date. Recently, our research data has shown that urotensin II is involved in the development of rat cardiac hypertrophy: Contractile response to human U II in rat and human pulmonary arteries was increased by endothelial factors, vascular tone, and the onset of pulmonary hypertension.
Solubility	The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
Chemical Bridge	Cys5-Cys10

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 9/25/2025

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