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Arg-Gly-Asp-Ser

Arg-Gly-Asp-Ser

Item no.	RP10861
Manufacturer	GenScript
Amount	5 mg
Category	Oncology Neuroscience Neural Adhesion Molecules By Cell Type Peptides & Proteins Cell Biology Cell Movement Cell Adhesion Cell Stainings ECM Peptides By Organ Colorectal Cancer
Type	Peptides
Specific against	other
Purity	> 95%
Sequence	RGDS ; {ARG}{GLY}{ASP}{SER}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP10861-R-G-D-S_RGDS, R-G-D-S, Arg-Gly-Asp-Ser, supports fibroblast attachment and inhibits fibronectin binding to platelets. It is the target sequence for syphilis spirochete adherence. RGDS increases ILK activity and the tyrosine phosphorylation of HMC proteins as well. In the case of tyrosine kinases, similar effects have been demonstrated in other cell types whereas the involvement of ILK, a serine-threonine kinase, in RGD effects has been less studied. To test the relevance of these two types of kinases in the stimulation of TGF-ß1 synthesis by RGDS, activities were blocked by pharmacological or transfection means. </td></tr><tr><th>Solubility</th><td colspan="7"> This peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store the peptide at -20C. Keep container tightly closed. </td></tr><tr><th>Notes</th><td colspan="7"> Exhibits cell attachment promoting activity</td></tr>
Similar products	Arg-Gly-Asp-Ser
Available
Country of Origin	USA
Storage Conditions	Store the peptide at -20C. Keep container tightly closed.
Description	R-G-D-S, Arg-Gly-Asp-Ser, supports fibroblast attachment and inhibits fibronectin binding to platelets. It is the target sequence for syphilis spirochete adherence. RGDS increases ILK activity and the tyrosine phosphorylation of HMC proteins as well. In the case of tyrosine kinases, similar effects have been demonstrated in other cell types whereas the involvement of ILK, a serine-threonine kinase, in RGD effects has been less studied. To test the relevance of these two types of kinases in the stimulation of TGF-ß1 synthesis by RGDS, activities were blocked by pharmacological or transfection means.
Solubility	This peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
Notes	Exhibits cell attachment promoting activity

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