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N-Formyl-Met-Leu-Phe

N-Formyl-Met-Leu-Phe

Item no.	RP12956
Manufacturer	GenScript
Amount	5 mg
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Peptides Other Lipid\Cholesterol Metabolism Modulators
Type	Peptides
Specific against	other
Purity	> 95%
Sequence	N-Formyl-MLF ; N-Formyl-{MET}{LEU}{PHE}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP12956-N-Formyl-Met-Leu-Phe_fMLF_N-Formyl-MLF, N-formyl-methionyl-leucyl-phenylalanine (fMLP), the chemotactic bacterial peptide, was able to specifically attenuate Ca2+ mobilization in human phagocytes induced by SAA, but only at very high concentrations. The bacterial peptide N-formyl-methionyl-leucyl-phenylalanine (fMLF) is one of the first identified and highly potent leukocyte chemoattractants. fMLF interacts with at least two human cell receptors formyl peptide receptor (FPR) and its variant formyl peptide receptor-like 1 (FPRL1), both are members of the seven transmembrane domain, G protein-coupled receptor (GPCR) family. </td></tr><tr><th>Solubility</th><td colspan="7"> Insoluble in water. Dissolve dry peptide in small quantity of DMSO. When completely dissolved further dilute with desired buffer. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C. Keep tightly closed. Store in a cool dry place. </td></tr>
Similar products	N-Formyl-Met-Leu-Phe
Available
Country of Origin	USA
Storage Conditions	Store at -20C. Keep tightly closed. Store in a cool dry place.
Description	N-formyl-methionyl-leucyl-phenylalanine (fMLP), the chemotactic bacterial peptide, was able to specifically attenuate Ca2+ mobilization in human phagocytes induced by SAA, but only at very high concentrations. The bacterial peptide N-formyl-methionyl-leucyl-phenylalanine (fMLF) is one of the first identified and highly potent leukocyte chemoattractants. fMLF interacts with at least two human cell receptors formyl peptide receptor (FPR) and its variant formyl peptide receptor-like 1 (FPRL1), both are members of the seven transmembrane domain, G protein-coupled receptor (GPCR) family.
Solubility	Insoluble in water. Dissolve dry peptide in small quantity of DMSO. When completely dissolved further dilute with desired buffer.

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