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SHU 9119

SHU 9119

Item no.	RP13311
Manufacturer	GenScript
Amount	0.2 mg
Category	Neuroscience Metabolism Glucose Homeostasis Regulation of Appetite Targets for Rodent Neurosciences Peptides & Proteins Obesity Cardiovascular Research Heart Failure Hypertension Peptides
Type	Peptides
Specific against	other
Purity	> 95%
Sequence	Ac-Nle-cyclo[Asp-His-D-Nal(2')-Arg-Trp-Lys]-NH2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP13311-SHU_9119, The efficacy and specificity of SHU-9119 as an MC3/MC4 receptor antagonist in the rat was first validated in vitro and in vivo. In vitro, in heterologous cells expressing either rat MC3-R or MC4-R, the major MCR subtypes expressed in brain, SHU-9119 showed no intrinsic agonism. </td></tr><tr><th>Solubility</th><td colspan="7"> Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Storage at -20C. Keep tightly closed. </td></tr><tr><th>Notes</th><td colspan="7"> Antagonist of rat MC3 and mouse MC4 receptors.</td></tr>
Similar products	SHU
Available
Country of Origin	USA
Storage Conditions	Storage at -20C. Keep tightly closed.
Description	The efficacy and specificity of SHU-9119 as an MC3/MC4 receptor antagonist in the rat was first validated in vitro and in vivo. In vitro, in heterologous cells expressing either rat MC3-R or MC4-R, the major MCR subtypes expressed in brain, SHU-9119 showed no intrinsic agonism.
Solubility	Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
C-Terminal	Amidation
Chemical Bridge	Asp2-Lys7
Notes	Antagonist of rat MC3 and mouse MC4 receptors.

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