G3-C12

Item no.	RP20329
Manufacturer	GenScript
Amount	1 mg
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Peptides By Organ Skin Cancer Breast Cancer Hepatic Cancer
Type	Peptides
Specific against	other
Purity	>95%
Sequence	ANTPCGPYTHDCPVKR ; {Ala}{Asn}{Thr}{Pro}{Cys}{Gly}{Pro}{Tyr}{Thr}{His}{Asp}{Cys}{Pro}{Val}{Lys}{Arg}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP20329-G3-C12, Galectin-3 is a member of the galectin family of beta-galactoside-binding animal lectins. Galectin-3 is overexpressed in a wide range of neoplasms and is associated with tumor growth and metastases. Given this fact, radiolabeled galectin-3-targeting molecules may be useful for the noninvasive imaging of tumors expressing galectin-3, as well as for targeted radionuclide therapy. In this study, the tumor cell-targeting and SPECT properties of a galectin-3-avid peptide identified from bacteriophage display were evaluated in human breast carcinoma cells and in human breast tumor-bearing mice. The galectin-3-avid peptide G3-C12 (ANTPCGPYTHDCPVKR) was synthesized with a Gly-Ser-Gly (GSG) linker at the amino terminus. </td></tr><tr><th>Purity</th><td colspan="7"> >95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C. </td></tr>
Similar products	G3-C12
Available
Country of Origin	USA
Storage Conditions	Store at -20C.
Description	Galectin-3 is a member of the galectin family of beta-galactoside-binding animal lectins. Galectin-3 is overexpressed in a wide range of neoplasms and is associated with tumor growth and metastases. Given this fact, radiolabeled galectin-3-targeting molecules may be useful for the noninvasive imaging of tumors expressing galectin-3, as well as for targeted radionuclide therapy. In this study, the tumor cell-targeting and SPECT properties of a galectin-3-avid peptide identified from bacteriophage display were evaluated in human breast carcinoma cells and in human breast tumor-bearing mice. The galectin-3-avid peptide G3-C12 (ANTPCGPYTHDCPVKR) was synthesized with a Gly-Ser-Gly (GSG) linker at the amino terminus.

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