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Atriopeptin III, rat

Atriopeptin III, rat

Item no.	RP11203-0.5
Manufacturer	GenScript
Amount	0.5mg
Category	Peptides & Proteins Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Peptides
Type	Peptides
Specific against	Rat
Purity	> 95%
Sequence	SSCFGGRIDRIGAQSGLGCNSFRY ; {SER}{SER}{CYS}{PHE}{GLY}{GLY}{ARG}{ILE}{ASP}{ARG}{ILE}{GLY}{ALA}{GLN}{SER}{GLY}{LEU}{GLY}{CYS}{ASN}{SER}{PHE}{ARG}{TYR}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP11203-Atriopeptin_III_rat, Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. Atriopeptin acts in opposition to angiotensin II in regulating renal, hemodynamic, and endocrine function. Atriopeptin is released in response to the increased pressure and mechanical stretch of the right atrium due to blood volume overload. Atriopeptin then acts at the nephron to increase salt and water excretion, lowering blood volume and blood pressure. The effects of atriopeptin III (AP III) on in vitro prepared afferent (AA) and efferent arterioles (EA) from rat kidneys were tested in a system in which lumen diameter could be measured. AP III (10(-13)-10(-7) M) had no effect on lumen diameter of AA that were not preconstricted. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C </td></tr>
Similar products	Atriopeptin
Available
Chemical Bridge	Disulfide bridge: Cys3-Cys19
Description	Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. Atriopeptin acts in opposition to angiotensin II in regulating renal, hemodynamic, and endocrine function. Atriopeptin is released in response to the increased pressure and mechanical stretch of the right atrium due to blood volume overload. Atriopeptin then acts at the nephron to increase salt and water excretion, lowering blood volume and blood pressure. The effects of atriopeptin III (AP III) on in vitro prepared afferent (AA) and efferent arterioles (EA) from rat kidneys were tested in a system in which lumen diameter could be measured. AP III (10(-13)-10(-7) M) had no effect on lumen diameter of AA that were not preconstricted.
Storage	Store at -20C
Product Origin	USA

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Amount: 0.5mg

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Delivery expected until 8/16/2024

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