Comparison

FGF-basic/FGF-2, Human European Partner

Manufacturer GenScript
Category
Type Proteins
Specific against Human
Format Sterile Filtered White lyophilized (freeze-dried) powder.
Amount 1mg
Item no. Z02734-1
Targets FOXD3, FGF9, FGF7, FGF6, FGF5, FGF4, FGF3, FGF2, FGF1
eClass 6.1 34160400
eClass 9.0 42020190
Available
Specificity
Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using murine NR6R/3T3 cells is less than 0.6 ng/ml, corresponding to a specific activity of 1.7 x 106 IU/mg.
Description
Fibroblast Growth Factor-basic (FGF-basic/FGF-2), is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF-1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor. Other homologous FGF belonging to the same family are int-2 ( FGF-3 ), FGF-5 , FGF-6 , K-FGF and KGF ( keratinocyte growth factor =FGF-7 ). All factors are products of different genes, some of which are Oncogene products ( FGF-3 , FGF-4 , FGF-5 ).
Endotoxin Level
Less than 0.02 EU/ug of, recombinant human FGF-basic/FGF-2, as determined by LAL method.
Formulation
Lyophilized from a 0.2um filtered concentrated, solution in PBS, pH 7.4.
M.W.
Approximately 16.5 kDa, a single non-glycosylated polypeptide chain containing 147 amino acids.
Note
This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Product Line
Cytokine, Chemokines & Growth Factors
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions.
Storage
This lyophilized recobinant human FGF-basic/FGF-2 is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Product Origin
USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
available

Delivery expected until 4/18/2024 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close