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Rabbit anti Human NPR-C (a.a. 199-212)

Rabbit anti Human NPR-C (a.a. 199-212)

Item no.	18-511-244581
Manufacturer	GENWAY
Amount	0,02 ml
Category	Antibodies Western Blot Cardiovascular Research Hypertension Primary Antibodies
Type	Antibody
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-12C832
Similar products	18-511-244581
Available
Genway ID:	GWB-12C832
Immunogen:	Synthetic human NPR-C (QEEGLHSIYSFDET) poly-Lysine conjugated.
Specificity:	Synthetic human NPR-C peptide (199-212)
Preservative:	None
Buffer:	Not applicable Applications Notes : Suitable for use in Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Description: Rabbit anti Human NPR-C (a. a. 199-212). Rabbit Antibody to Human Natriuretic Peptide Receptor-C (NPR-C) amino acids 199-212
Function:	Receptor for natriuretic peptide hormones. Has broad specificity and can bind several distinct natriuretic peptides including atrial natriuretic peptide (NPPA) and brain natriuretic peptide (NPPB). Does not have guanylate cyclase activity.
Subunit:	Homodimer; disulfide-linked. Dimers can also be formed through the C-terminal cysteine of isoform 2.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Miscellaneous:	There seem to be at least three natriuretic peptide hormone receptors: two with guanylate cyclase activity (NPR1/ANP-A and NPR2/ANP-B) and one (NPR3/ANP-C) which is probably responsible for the clearance of natriuretic peptides from the circulation without a role in signal transduction.
Miscellaneous:	Has low affinity for peptide hormones in the absence of bound chloride.
Similarity:	Belongs to the ANF receptor family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0,02 ml

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Delivery expected until 9/11/2025

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