RABBIT ANTI HUMAN TRHR (C-TERMINAL)

TRHR (C-TERMINAL)

Phosphate buffered saline pH7. 7

Synthetic peptide: C-terminal domain of human Thyrotropin-releasing hormone receptor conjugated to Keyhole Limpet Hemocyanin (KLH).

Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Subcellular locationCell membrane; Multi-pass membrane protein. Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. 1. Bradstock K. F. et al. (1985) Human myeloid differentiation antigens identified by monoclonal antibodies: Expression on leukaemic cells. Pathology 17: 392-399. 2. Bradstock K. F. et al. (1985) Myeloid progenitor surface antigen identified by monoclonal antibody. Br. J. Haematol. 61: 11-20. 3. Favaloro E. J. et al. (1988) Further characterisation of myeloid antigens (\' gp160 95\' \' gp150\' and \' gp567\' ): Investigation of epitope heterogeneity and non-haemopoietic distribution using panels of monoclonal antibodies belonging to CD11b CD13 and CD33. Br. J. Haematol. 69: 163-171. 4. Favaloro E. J. (1991) CD13 (\' gp150\' Aminopeptidase-N): Co-expression on human endothelial and haemopoietic cells with conservation of functional activity. Immunol. Cell Biol. 69: 253-260. 5. Favaloro E. J. et al. (1993) The hepatobiliary disease marker serum alanine-aminopeptidase predominantly comprises an isoform of the haematological myeloid differentiation antigen and leukaemia marker CD13/gp150. Clin. Chim. Acta 220: 81-90. 6. Favaloro E. J. et al. (1993) CD13 (gp150; aminopeptidase-N): Predominant functional activity in blood is localised to plasma and is not cell surface associated. Exp. Hematol. 21: 1695-1701. [1] \" Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA. \" Olsen J. Cowell G. M. Koenigshoefer E. Danielsen E. M. Moeller J. Laustsen L. Hansen O. C. Welinder K. G. Engberg J. Hunziker W. Spiess M. Sjoestroem H. Noren O. FEBS Lett. 238:307-314(1988) [PubMed: 2901990] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] VARIANTS GLN-86 AND MET-603. Tissue: Intestine. [2] \" Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. \" Look A. T. Ashmun R. A. Shapiro L. H. Peiper S. C. J. Clin. Invest. 83:1299-1307(1989) [PubMed: 2564851] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] PROTEIN SEQUENCE OF 2-21 VARIANT GLN-86. [3] \" Analysis of the DNA sequence and duplication history of human chromosome 15. \" Zody M. C. Garber M. Sharpe T. Young S. K. Rowen L. O\' Neill K. Whittaker C. A. Kamal M. Chang J. L. Cuomo C. A. Dewar K. FitzGerald M. G. Kodira C. D. Madan A. Qin S. Yang X. Abbasi N. Abouelleil A. Arachchi H. M. Baradarani L. Birditt B. Bloom S. Bloom T. Borowsky M. L. Burke J. Butler J. Cook A. DeArellano K. DeCaprio D. Dorris L. III Dors M. Eichler E. E. Engels R. Fahey J. Fleetwood P. Friedman C. Gearin G. Hall J. L. Hensley G. Johnson E. Jones C. Kamat A. Kaur A. Locke D. P. Madan A. Munson G. Jaffe D. B. Lui A. Macdonald P. Mauceli E. Naylor J. W. Nesbitt R. Nicol R. O\' Leary S. B. Ratcliffe A. Rounsley S. She X. Sneddon K. M. B. Stewart S. Sougnez C. Stone S. M. Topham K. Vincent D. Wang S. Zimmer A. R. Birren B. W. Hood L. Lander E. S. Nusbaum C. Nature 440:671-675(2006) [PubMed: 16572171] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [4] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pancreas. [5] \" Separate promoters control transcription of the human aminopeptidase N gene in myeloid and intestinal epithelial cells. \" Shapiro L. H. Ashmun R. A. Roberts W. M. Look A. T. J. Biol. Chem. 266:11999-12007(1991) [PubMed: 1675638] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15. Tissue: Intestinal epithelium. [6] \" Genomic organisation of aminopeptidase N. \" Eiz-Vesper B. Fuchs N. Gottschalk D. Mueller K. Reuter S. Blasczyk R. Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-479 AND 524-967 VARIANT GLN-86. Tissue: Peripheral blood. [7] \" Identification of an alanine aminopeptidase in human maternal serum as a membrane-bound aminopeptidase N. \" Watanabe Y. Iwaki-Egawa S. Mizukoshi H. Fujimoto Y. Biol. Chem. Hoppe-Seyler 376:397-400(1995) [PubMed: 7576235] [Abstract]Cited for: PROTEIN SEQUENCE OF 2-20 AND 70-81. [8] \" Cholesterol crystallization-promoting activity of aminopeptidase-N isolated from the vesicular carrier of biliary lipids. \" Nunez L. Amigo L. Rigotti A. Puglielli L. Mingrone G. Greco A. V. Nervi F. FEBS Lett. 329:84-88(1993) [PubMed: 8102610] [Abstract]Cited for: PROTEIN SEQUENCE OF 2-18. [9] \" Purification and characterization of aminopeptidase N from human plasma. \" Tokioka-Terao M. Hiwada K. Kokubu T. Enzyme 32:65-75(1984) [PubMed: 6149934] [Abstract]Cited for: CHARACTERIZATION SUBUNIT. [10] \" Variable O-glycosylation of CD13 (aminopeptidase N). \" O\' Connell P. J. Gerkis V. d\' Apice A. J. F. J. Biol. Chem. 266:4593-4597(1991) [PubMed: 1705556] [Abstract]Cited for: GLYCOSYLATION.