Comparison

GOAT ANTI HUMAN IgG (Fc)

Item no. 18-783-314033
Manufacturer GENWAY
Amount 1 ml
Category
Type Antibody
Specific against Human (Homo sapiens)
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-8E616C
Similar products 18-783-314033
Available
Genway ID:
GWB-8E616C
Specificity:
IgG (Fc)
Isotype:
Polyclonal IgG
Buffer Solution:
TRIS buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3)
Immunogen:
Purified human IgG (Fc)
Specificity:
Recognizes human IgG (Fc). This reagent is available in bulk quantities and may be made available in other formats. Please enquire for further details. Recommended Secondary Antibodies: Rabbit Anti Goat IgG (Fc)
Subcellular Location:
Secreted. Involvement in diseaseChromosomal aberrations involving IGHG1 may be a cause of multiple myeloma [MIM:254500]. Translocation t(11; 14)(q13; q32) with CCND1; translocation t(4; 14)(p16. 3; q32. 3) with FGFR3; translocation t(6; 14)(p25; q32) with IRF4.
Miscellaneous:
Nie has the G1M(17) allotypic marker 97-K and the G1M1 markers 239-D and 241-L. KOL and EU sequences have the G1M3 marker and the G1M (non-1) markers. Nie also differs in the amidation states of 35 116 198 269 and 272. EU also differs in the amidation states of residues 155 166 177 195 198 269 and 272 and in the order of residues 268-272. KOL also differs in the amidation states of residues 198 267 and 272. Sequence cautionThe sequence AAC82527. 1 differs from that shown. Reason: Erroneous initiation. 1. Kadowaki N. et al. (2000) Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J. Exp. Med. 192: 219-225. 2. Butler D. et al. (1997) DBA/1 mice expressing the human TNF-alpha transgene develop a severe erosive arthritis: characterization of the cytokine cascade and cellular composition. J. Immunol. 159: 2867-2876. 3. Abrams J. (1995) Immunoenzymatic assay of mouse and human cytokines using NIP-labelled anti-cytokine antibodies. Current Protocols in Immunology. Edited by Coligan J. et al. John Wiley and Sons. 4. Evans H. G. et al. (2009) In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses. Proc Natl Acad Sci U S A. 106: 6232-7. 5. Vujanovic L. et al. (2010) Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15. Blood. 116: 575-83. [1] \" Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome. \" Nedospasov S. A. Shakhov A. N. Turetskaya R. L. Mett V. A. Azizov M. M. Georgiev G. P. Korobko V. G. Dobrynin V. N. Filippov S. A. Bystrov N. S. Boldyreva E. F. Chuvpilo S. A. Chumakov A. M. Shingarova L. N. Ovchinnikov Y. A. Cold Spring Harb. Symp. Quant. Biol. 51:611-624(1986) [PubMed: 3555974] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [2] \" Human tumour necrosis factor: precursor structure expression and homology to lymphotoxin. \" Pennica D. Nedwin G. E. Hayflick J. S. Seeburg P. H. Derynck R. Palladino M. A. Kohr W. J. Aggarwal B. B. Goeddel D. V. Nature 312:724-729(1984) [PubMed: 6392892] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. [3] \" Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. \" Shirai T. Yamaguchi H. Ito H. Todd C. W. Wallace R. B. Nature 313:803-806(1985) [PubMed: 3883195] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. [4] \" Human lymphotoxin and tumor necrosis factor genes: structure homology and chromosomal localization. \" Nedwin G. E. Naylor S. L. Sakaguchi A. Y. Smith D. H. Jarrett-Nedwin J. Pennica D. Goeddel D. V. Gray P. W. Nucleic Acids Res. 13:6361-6373(1985) [PubMed: 2995927] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. [5] \" Molecular cloning of the complementary DNA for human tumor necrosis factor. \" Wang A. M. Creasey A. A. Ladner M. B. Lin L. S. Strickler J. van Arsdell J. N. Yamamoto R. Mark D. F. Science 228:149-154(1985) [PubMed: 3856324] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [6] \" Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor. \" Marmenout A. Fransen L. Tavernier J. van der Heyden J. Tizard R. Kawashima E. Shaw A. Johnson M. J. Semon D. Mueller R. Ruysschaert M. -R. van Vliet A. Fiers W. Eur. J. Biochem. 152:515-522(1985) [PubMed: 3932069] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [7] \" Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. \" Iris F. J. M. Bougueleret L. Prieur S. Caterina D. Primas G. Perrot V. Jurka J. Rodriguez-Tome P. Claverie J. -M. Dausset J. Cohen D. Nat. Genet. 3:137-145(1993) [PubMed: 8499947] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [8] \" A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC. \" Neville M. J. Campbell R. D. J. Immunol. 162:4745-4754(1999) [PubMed: 10202016] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [9] \" Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. \" Xie T. Rowen L. Aguado B. Ahearn M. E. Madan A. Qin S. Campbell R. D. Hood L. Genome Res. 13:2621-2636(2003) [PubMed: 14656967] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [10] \" Homo sapiens 2 229 817bp genomic DNA of 6p21. 3 HLA class I region. \" Shiina S. Tamiya G. Oka A. Inoko H. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ml
Available: In stock
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