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Human Growth Hormone

Human Growth Hormone

Item no.	20-511-241019
Manufacturer	GENWAY
Amount	0.1mg
Category	Metabolism Diabetes Antibodies ELISA Primary Antibodies
Type	Antibody
Applications	ELISA
Clone	GhB9
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-47C2D0
Similar products	20-511-241019
Available
Genway ID:	GWB-47C2D0
Isotype:	IgG1
Clone:	GhB9Host Animal: Mouse. Hybridization of X63-Ag8-653
Type of Product:	Monoclonal Antibodies to Hormones and Steroids
Concentration:	6mg/ml (OD280nm. E0. 1%=1. 4)Preservatives: NaN3
Buffer:	PBS. pH 7. 4Applications Notes : Suitable for use in ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Recommended pair for sandwich immunoassay:. Capture Detection. 20-511-241015 20-511-241019
Warning:	This product contains sodium azide which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing flush with copious volumes of water to prevent azide build-up in drains. MAb to Human Growth Hormone. Monoclonal Antibody to Human Growth Hormone (hGH)
Function:	Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Subunit:	Monomer dimer trimer tetramer and pentamer disulfide-linked or non-covalently associated in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex.
Subcellular Location:	Secreted.
Disease:	Defects in GH1 are a cause of isolated growth hormone deficiency type IB (IGHD IB) [MIM:262400]; also known as pituitary dwarfism I. IGHD IB is an autosomal recessive deficiency of GH which causes short stature.
Disease:	Defects in GH1 are the cause of Kowarski syndrome [MIM:262650]; also known as pituitary dwarfism VI.
Disease:	Defects in GH1 are a cause of isolated growth hormone deficiency type II (IGHD II) [MIM:173100]. IGHD II is an autosomal dominant deficiency of GH which causes short stature.
Disease:	Defects in GH1 may be a cause of short stature [MIM:604271]. Short stature is defined by a subnormal rate of growth. Pharmaceutical: Available under the names Nutropin or Protropin (Genentech) Norditropin (Novo Nordisk) Genotropin (Pharmacia Upjohn) Humatrope (Eli Lilly) and Saizen or Serostim (Serono). Used for the treatment of growth hormone deficiency and for Turner\' s syndrome.
Miscellaneous:	Circulating GH shows a great heterogeneity due to alternative splicing differential post-translational modifications of monomeric forms oligomerization optional binding to 2 different GH-binding proteins and potentially proteolytic processing.
Similarity:	Belongs to the somatotropin/prolactin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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