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Human CD8 beta

Human CD8 beta

Item no.	20-511-241082
Manufacturer	GENWAY
Amount	0,2 mg
Category	Oncology Antibodies By Cell Type Hematology Leukemia Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	FC, IP, IHC
Clone	2ST8. 5H7
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-8DC1B0
Similar products	20-511-241082
Available
Genway ID:	GWB-8DC1B0
Isotype:	IgG2a. k
Clone:	2ST8. 5H7Host Animal: Mouse. Hybridization of NS1 myeloma cells with spleen cells from Balb/c mice.
Immunogen:	Normal human T cells
Specificity:	Recognizes an epitope of the CD8 beta molecule that depends upon the expression of both CD8 alpha and CD8 beta chains. (1-3) Immunoprecipitates the human complex CD8 alpha/beta (30-32kDa) from cell lines expressing the alpha and beta cDNA. (2)
Type of Product:	Monoclonal Antibodies to Human CDs
Concentration:	0. 2mg/ml (prior to lyophilization)
Buffer:	Lyophilized from PBS containing 1mg/ml BSAApplications Notes : Flow cytometry and fluorescent microscopy (2ug / 5 x 105 cells/test or 100ul of whole blood). Immunoprecipitation. Research studies of structural and/or functional characteristics of protein chains in multimeric CD8 complexes. . Functional studies of cells expressing heterodimeric alpha/beta CD8 complex. . Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. MAb to Human CD8 beta. Monoclonal Antibody to Human CD8 beta
Function:	Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.
Subunit:	In general heterodimer of an alpha and a beta chain linked by two disulfide bonds.
Subcellular Location:	Cell membrane; Single-pass type I membrane protein.
Subcellular Location:	Isoform 3: Secreted (Probable).
Ptm:	Phosphorylated as a consequence of T-cell activation (Potential).
Similarity:	Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0,2 mg

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Delivery expected until 8/28/2025

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