Comparison

Human IgA (Secretory)

Item no. 20-511-241264
Manufacturer GENWAY
Amount 1mg
Category
Type Antibody
Applications ELISA
Clone B781M
Specific against Human (Homo sapiens)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-70630E
Similar products 20-511-241264
Available
Genway ID:
GWB-70630E
Isotype:
IgG1
Clone:
B781MHost Animal: Mouse
Immunogen:
Purified Human IgA
Specificity:
Human IgA Secretory Component. Reacts against all human IgA subtypes.
Type of Product:
Monoclonal Antibodies to Human Immunoglobulins
Concentration:
1mg/ml (prior to lyophilization)
Buffer:
Lyophilized from PBSApplications Notes : Suitable for use in ELISA. By direct ELISA 1:20 000 dilution will yield > 1. 0 O. D. using alkaline phosphatase conjugated Rabbit anti-mouse Ig. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. MAb to Human IgA (Secretory). Monoclonal Antibody to Human Immunoglobulin A (IgA) Secretory Component
Function:
Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:
Monomeric or polymeric.
Ptm:
3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:
A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:
Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
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