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Rhodamine Conjugated Affinity Purified Anti-HUMAN IgA (alpha chain) (RABBIT)

Rhodamine Conjugated Affinity Purified Anti-HUMAN IgA (alpha chain) (RABBIT)

Item no.	25-732-294170
Manufacturer	GENWAY
Amount	1 mg
Category	Oncology Antibodies By Cell Type Hematology Lymphoma Immunohistochemistry Western Blot ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-3CF070
Similar products	25-732-294170
Available
Genway ID:	GWB-3CF070
Antigen:	IgA or Alpha Heavy Chain
Immunogen:	Human IgA alpha chain Family: Affinity PurifiedFraction: Affinity Purified IgGPurity
Note:	This product was prepared from monospecific antiserum by immunoaffinity chromatography using Human IgA coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by mmunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum Human IgA and Human Serum. Specificity was confirmed by ELISA at less than 1% cross reactivity against other human heavy or light chain isotypes.
Conjugation:	RhodamineConjugation Reference: J. A. Titus et al. J. Immunol. Methods 50; 193 1982.
Application:	suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency. Antibody
Concentration:	1. 0 mg/ml (by UV absorbance at 280 nm)Label: Tetramethylrhodamine isothiocyanante (TRITC) (Molecular Weight 444 daltons)
Stabilizer:	10 mg/ml Bovine Serum Albumin (BSA) IgG and Protease free
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 9/11/2025

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