Comparison

Rat Anti-Mouse CD49e/VLA-5

Item no. 20-787-275464
Manufacturer GENWAY
Amount 0.5 mg
Category
Type Antibody
Applications FC, IHC
Clone 5H10. 27
Specific against Mouse (Murine, Mus musculus)
Host Rat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-D52CAC
Similar products 20-787-275464
Available
Genway ID:
GWB-D52CAC
Isotype:
Rat (Lewis) IgG2a kappa
Clone:
5H10. 27
Immunogen:
C57BL/6 x A/J F1 mouse mast cell line MC/9 1
Characterization:
To insure acceptable performance each batch of product is tested by flow cytometry to conform to characteristics of a standard reference reagent.
Specificity:
5 subunit of the integrin 51 fibronectin receptor The monoclonal antibody 5H10-27 reacts with the 5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes activated T cells mast cells and a variety of mouse cell lines. 1-5 Soluble 5H10-27 antibody inhibits VLA-5-mediated functions in vitro. 1 2-4 6 Immobilized 5H10-27 has also been demonstrated to co-stimulate the proliferative response of CD8+ T cells to plate-bound anti- CD3 monoclonal antibody
Working Dilution:
Flow Cytometry: 1 ug/106 cells
Warning:
Conjugates contain sodium azide which is very toxic if ingested or inhaled. Avoid contact with skin eyes or clothing. Wear eye or face protection when handling. If skin or eye contact occurs wash with copious amounts of water. If ingested or inhaled contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing. 1. Kinashi T. and T. A. Springer. 1994. Blood Cells 20:25. 2. Halvorson M. J. and J. E. Coligan. 1995. J. Immunol. 155:4567. 3. Rich S. N. van Nood and H. -M Lee. 1996. J. Immunol. 157:2916. 4. Uhlenkott C. E. J. C. Huijzer D. J. Cardeiro C. A. Elstad and G. G. Meadows. 1996. Clin. Exp. Metastasis 14:125. 5. Hemler M. E. 1990. Annu. Rev. Immunol. 8:365. 6. Schultz J. F. and D. R. Armant. 1995. J. Biol Chem. 270:11522. 7. nology Associates Inc. Unpublished observations.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.5 mg
Available: In stock
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