TCEA2 (transcription elongation factor A (SII). 2)

Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human TCEA2.

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. The protein encoded by TCEA2 is found in the nucleus. where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at tem

Interacts with the basal transcription factor GTF2B. Interacts with REXO1.

Testis and ovary specific.

Contains 1 TFIIS central domain.

Contains 1 TFIIS-type zinc finger. Summary: The protein encoded by this gene is found in the nucleus where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. Sijbrandi. R. . et al. . (2002) Nucleic Acids Res. 30(11). 2290-8.