CACNG1 (calcium channel. voltage-dependent. gamma subunit 1)

Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human CACNG1.

Signal Protein

This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex.

Membrane; Multi-pass membrane protein.

Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. Summary: L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits gamma and is one of several gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1 4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This protein is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes. Chu. P. J. . et al. . Gene 280 (1-2). 37-48 (2001).